Study Suggests GLP-1 Medications May Reduce Physical Activity

Study Suggests GLP-1 Medications May Reduce Physical Activity

Source: FOX News

Summary

A new study found that adults with obesity who lost weight with GLP-1 medications, such as Ozempic or Wegovy, significantly reduced their physical activity. The study, presented at ENDO 2026, analyzed data from 753 participants and found that the average number of steps decreased from 5,047 to 4,487 per day, and moderate-to-vigorous physical activity fell from 28 to 22 minutes per day. The study’s lead author, Sajana Maharjan, MD, emphasized that physical activity is essential for preserving strength and long-term health, especially when taking GLP-1 medications.


Our Reading

The advice sounds familiar.

The study’s findings suggest that GLP-1 medications may lead to decreased physical activity, contradicting the assumption that weight loss would increase motivation to exercise. The study’s limitations, such as its retrospective and observational design, are acknowledged. The importance of exercise in preserving lean muscle mass and metabolic health is emphasized by experts. The study’s results highlight the need for targeted interventions that encourage physical activity alongside medication for obesity.

It’s not the first time we’ve heard that weight loss doesn’t always lead to increased physical activity.


Author: Evan Null