Source: Fox News
Summary
A study led by Brown University researchers found that older adults who received the shingles vaccine Shingrix had a 24% lower risk of dementia over four years compared to those who did not. The study, published in The Annals of Internal Medicine, analyzed data from over 509,926 U.S. adults aged 66 and older. While the findings suggest an association, they do not prove the vaccine directly prevents dementia. Experts noted the results align with previous studies, but the vaccine is not currently considered a treatment for cognitive decline. The study was funded by GSK, the manufacturer of Shingrix, though the company had no role in its design or publication.
Our Reading
This guidance has been heard before.
Shingles vaccine linked to lower dementia risk, again.
Studies show similar results, but no proof of cause.
Experts say it’s not a treatment, just a possible association.
Health advice keeps shifting, but the same themes return.
Author: Evan Null
Shingles Vaccine and Dementia Risk
A recent study from Brown University suggests that the shingles vaccine, Shingrix, may be associated with a lower risk of dementia in older adults. The research, published in The Annals of Internal Medicine, analyzed data from over 509,926 U.S. adults aged 66 and older. The study found that those who received at least one dose of Shingrix had a 24% reduced risk of dementia over four years compared to those who did not. However, the study does not prove that the vaccine directly prevents dementia.
Scientific Literature Builds on the Findings
Dr. Ajeet Sodhi, a clinical neurologist not involved in the study, noted that this is one of several studies showing similar results. He stated that the findings align with a growing body of research, though the vaccine is not currently considered a treatment for cognitive decline. Sodhi emphasized that while the association is significant, more research is needed to determine if the vaccine has a direct preventive effect on dementia.
Possible Explanations for the Association
Researchers have proposed several explanations for the link between the shingles vaccine and lower dementia risk. One theory is that the vaccine prevents shingles and its complications, including vascular events like stroke, which can contribute to vascular dementia. The varicella-zoster virus, which causes shingles, is also linked to long-term nerve pain and other health issues that may impact cognitive function.
Shingles Vaccine Benefits Beyond Dementia
In addition to the potential link to dementia, recent studies have also shown that the shingles vaccine may reduce the risk of cardiovascular and cerebrovascular diseases, including heart attacks and strokes. Dr. Sodhi highlighted these findings as further evidence of the vaccine’s broader health benefits, though he stressed that it is not currently classified as a treatment for cognitive decline.
Recommendations and Future Research
The Centers for Disease Control and Prevention recommends two doses of Shingrix for adults 50 and older, as well as those who are immunocompromised. While the vaccine is approved to prevent shingles and its complications, it is not approved for the prevention or treatment of dementia. Experts advise individuals concerned about memory loss or family medical history to consult a doctor early for evaluation and potential treatment.
